BDBM152922 US8993586, 119

SMILES: CCCNc1nccc2ccc(cc12)C(=O)N1CCC2(CC1)Cc1cn(nc1C(=O)N2)C(C)(C)C

InChI Key: InChIKey=VFVIIGJPUABWCI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 152922   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM152922 (US8993586, 119) Show SMILES CCCNc1nccc2ccc(cc12)C(=O)N1CCC2(CC1)Cc1cn(nc1C(=O)N2)C(C)(C)C Show InChI InChI=1S/C27H34N6O2/c1-5-11-28-23-21-15-19(7-6-18(21)8-12-29-23)25(35)32-13-9-27(10-14-32)16-20-17-33(26(2,3)4)31-22(20)24(34)30-27/h6-8,12,15,17H,5,9-11,13-14,16H2,1-4H3,(H,28,29)(H,30,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description Preparation of rhACC2. Human ACC2 inhibition was measured using purified recombinant human ACC2 (hrACC2). Briefly, a full length Cytomax clone of ACC...				US Patent US8993586 (2015) BindingDB Entry DOI: 10.7270/Q2N58K43
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 1 (ACC1) (Homo sapiens (Human))	BDBM152922 (US8993586, 119) Show SMILES CCCNc1nccc2ccc(cc12)C(=O)N1CCC2(CC1)Cc1cn(nc1C(=O)N2)C(C)(C)C Show InChI InChI=1S/C27H34N6O2/c1-5-11-28-23-21-15-19(7-6-18(21)8-12-29-23)25(35)32-13-9-27(10-14-32)16-20-17-33(26(2,3)4)31-22(20)24(34)30-27/h6-8,12,15,17H,5,9-11,13-14,16H2,1-4H3,(H,28,29)(H,30,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	7.5	n/a
Pfizer Inc. US Patent					Assay Description Preparation of rhACC1. Two liters of SF9 cells, infected with recombinant baculovirus containing full length human ACC1 cDNA, were suspended in ice-c...				US Patent US8993586 (2015) BindingDB Entry DOI: 10.7270/Q2N58K43
					More data for this Ligand-Target Pair