null
SMILES: FC(F)(F)c1cc(C2CC2)n(n1)-c1ccc(NC(=O)Cn2nc3ccccc3n2)cc1
InChI Key: InChIKey=ZUDNUHAUOQUVAS-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Calcium release-activated calcium channel protein 1 (Homo sapiens (Human)) | BDBM152938 (US8993612, 21) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 139 | n/a | n/a | n/a | n/a | n/a | 37 |
Rhizen Pharmaceuticals SA US Patent | Assay Description Inhibition of CRAC channels was determined following thapsigargin (Sigma, Cat # T9033) induced endoplasmic calcium release in Jurkat cells. (see Yasu... | US Patent US8993612 (2015) BindingDB Entry DOI: 10.7270/Q2CN72NK | |||||||||||
More data for this Ligand-Target Pair |