BDBM15355 2-methyl-3-nitro-N-[3-(trifluoromethyl)phenyl]benzamide::Asinex compound no. 10

SMILES: Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key: InChIKey=KQEQFJYYETUTSQ-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 15355   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate Dehydrogenase (DHODH) (Plasmodium falciparum)	BDBM15355 (2-methyl-3-nitro-N-[3-(trifluoromethyl)phenyl]benz...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C15H11F3N2O3/c1-9-12(6-3-7-13(9)20(22)23)14(21)19-11-5-2-4-10(8-11)15(16,17)18/h2-8H,1H3,(H,19,21)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	8.0	22
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate Dehydrogenase (DHODH) Mutant (H185A) (Plasmodium falciparum)	BDBM15355 (2-methyl-3-nitro-N-[3-(trifluoromethyl)phenyl]benz...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C15H11F3N2O3/c1-9-12(6-3-7-13(9)20(22)23)14(21)19-11-5-2-4-10(8-11)15(16,17)18/h2-8H,1H3,(H,19,21)	PDB MMDB B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate Dehydrogenase (DHODH) Mutant (R265A) (Plasmodium falciparum)	BDBM15355 (2-methyl-3-nitro-N-[3-(trifluoromethyl)phenyl]benz...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C15H11F3N2O3/c1-9-12(6-3-7-13(9)20(22)23)14(21)19-11-5-2-4-10(8-11)15(16,17)18/h2-8H,1H3,(H,19,21)	PDB MMDB B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate Dehydrogenase (DHODH) (Homo sapiens (Human))	BDBM15355 (2-methyl-3-nitro-N-[3-(trifluoromethyl)phenyl]benz...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C15H11F3N2O3/c1-9-12(6-3-7-13(9)20(22)23)14(21)19-11-5-2-4-10(8-11)15(16,17)18/h2-8H,1H3,(H,19,21)	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair