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SMILES: O=C(N[C@@H](Cc1ccc(cc1)-c1ccc2C(=O)OCc2c1)C#N)[C@H]1N[C@@H]2CC[C@H]1C2

InChI Key: InChIKey=PFKMGTMZODMICS-UFGBVDADSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 153583   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dipeptidyl peptidase 1


(Homo sapiens (Human))		BDBM153583
PNG
(US8999975, 100)
Show SMILES O=C(N[C@@H](Cc1ccc(cc1)-c1ccc2C(=O)OCc2c1)C#N)[C@H]1N[C@@H]2CC[C@H]1C2 |r|
Show InChI InChI=1S/C24H23N3O3/c25-12-20(27-23(28)22-17-5-7-19(11-17)26-22)9-14-1-3-15(4-2-14)16-6-8-21-18(10-16)13-30-24(21)29/h1-4,6,8,10,17,19-20,22,26H,5,7,9,11,13H2,(H,27,28)/t17-,19+,20-,22-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 2n/an/an/an/a6.025



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...

US Patent US8999975 (2015)


BindingDB Entry DOI: 10.7270/Q22806BZ
More data for this
Ligand-Target Pair