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BDBM153700 L-VC26

SMILES: CC1(C)S[C@H]2CS[C@H](CS)N2[C@@H]1C(O)=O

InChI Key: InChIKey=IKSIYRPSHTUWIX-HNBBVXEKNA-N

Data: 2 KI

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 153700   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metallo-beta-lactamase VIM-2 (VIM-2)


(Pseudomonas aeruginosa (g-Proteobacteria))
BDBM153700
PNG
(L-VC26)
Show SMILES CC1(C)S[C@H]2CS[C@H](CS)N2[C@@H]1C(O)=O |r|
Show InChI InChI=1/C9H15NO2S3/c1-9(2)7(8(11)12)10-5(3-13)14-4-6(10)15-9/h5-7,13H,3-4H2,1-2H3,(H,11,12)/t5-,6+,7-/s2
PDB

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
PDB
UniChem
Article
PubMed
3.80E+3n/an/an/an/an/an/an/an/a



Louis Stokes Cleveland Veterans Affairs Medical Center



Assay Description
The Ki for each inhibitor was determined by direct competition assays under steady-state conditions. The initial velocity was measured in the presenc...


Biochemistry 54: 3183-96 (2015)


Article DOI: 10.1021/acs.biochem.5b00106
BindingDB Entry DOI: 10.7270/Q2513WZZ
More data for this
Ligand-Target Pair
Metallo-beta-lactamase VIM-24 (VIM-24)


(Klebsiella pneumoniae (Enterobacteria))
BDBM153700
PNG
(L-VC26)
Show SMILES CC1(C)S[C@H]2CS[C@H](CS)N2[C@@H]1C(O)=O |r|
Show InChI InChI=1/C9H15NO2S3/c1-9(2)7(8(11)12)10-5(3-13)14-4-6(10)15-9/h5-7,13H,3-4H2,1-2H3,(H,11,12)/t5-,6+,7-/s2
PDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
PDB
UniChem
Article
PubMed
4.90E+3n/an/an/an/an/an/an/an/a



Louis Stokes Cleveland Veterans Affairs Medical Center



Assay Description
The Ki for each inhibitor was determined by direct competition assays under steady-state conditions. The initial velocity was measured in the presenc...


Biochemistry 54: 3183-96 (2015)


Article DOI: 10.1021/acs.biochem.5b00106
BindingDB Entry DOI: 10.7270/Q2513WZZ
More data for this
Ligand-Target Pair