BDBM153858 US8999981, A103

SMILES: C[C@H]1CN2CCC[C@H]2CC1C(=O)N1Cc2c(NC(=O)c3csc(Br)n3)n[nH]c2C1(C)C

InChI Key:

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 153858   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PKC alpha and beta-2 (Homo sapiens (Human))	BDBM153858 (US8999981, A103) Show SMILES C[C@H]1CN2CCC[C@H]2CC1C(=O)N1Cc2c(NC(=O)c3csc(Br)n3)n[nH]c2C1(C)C |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	12.9	-10.9	n/a	n/a	n/a	n/a	n/a	7.4	30
Pfizer Inc.; Pfizer Products Inc. US Patent					Assay Description Protein Kinase C beta 2 (PKC beta II) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US8999981 (2015) BindingDB Entry DOI: 10.7270/Q2RR1X0K
					More data for this Ligand-Target Pair