BDBM153888 US8999981, A133
SMILES: C[C@H]1CN(C)C2(CCC2)CN1C(=O)N1Cc2c(NC(=O)c3ccccn3)n[nH]c2C1(C)C
InChI Key:
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PKC alpha and beta-2 (Homo sapiens (Human)) | BDBM153888 (US8999981, A133) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 8.58 | -11.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 30 |
Pfizer Inc.; Pfizer Products Inc. US Patent | Assay Description Protein Kinase C beta 2 (PKC beta II) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe... | US Patent US8999981 (2015) BindingDB Entry DOI: 10.7270/Q2RR1X0K | |||||||||||
More data for this Ligand-Target Pair |