BDBM15406 4-ethyl-N-[4-hydroxy-3-(2-hydroxynaphthalen-1-yl)phenyl]benzene-1-sulfonamide::naphthol compound 9

SMILES: CCc1ccc(cc1)S(=O)(=O)Nc1ccc(O)c(c1)-c1c(O)ccc2ccccc12

InChI Key: InChIKey=TUKGQHYMGHPXPZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15406   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heat shock protein HSP 90-beta (Homo sapiens (Human))	BDBM15406 (4-ethyl-N-[4-hydroxy-3-(2-hydroxynaphthalen-1-yl)p...) Show SMILES CCc1ccc(cc1)S(=O)(=O)Nc1ccc(O)c(c1)-c1c(O)ccc2ccccc12 |(2.24,12.15,;2.23,10.61,;.9,9.84,;-.43,10.61,;-1.77,9.84,;-1.77,8.3,;-.43,7.53,;.9,8.3,;-3.1,7.53,;-3.87,8.86,;-2.33,6.19,;-4.43,6.76,;-4.43,5.22,;-5.77,4.45,;-5.77,2.9,;-4.43,2.13,;-4.43,.59,;-3.1,2.9,;-3.1,4.45,;-1.77,2.13,;-1.77,.59,;-3.1,-.18,;-.43,-.18,;.9,.59,;.9,2.13,;2.23,2.91,;2.23,4.45,;.9,5.22,;-.43,4.45,;-.43,2.91,)| Show InChI InChI=1S/C24H21NO4S/c1-2-16-7-11-19(12-8-16)30(28,29)25-18-10-14-22(26)21(15-18)24-20-6-4-3-5-17(20)9-13-23(24)27/h3-15,25-27H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	7.4	22
Vernalis (R&D) Ltd					Assay Description The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...				Bioorg Med Chem Lett 15: 5187-91 (2005) Article DOI: 10.1016/j.bmcl.2005.08.092 BindingDB Entry DOI: 10.7270/Q2HH6H9Z
					More data for this Ligand-Target Pair