BDBM154566 N-(3-(Tert-butylamino)propyl)-4-(trifluoromethyl)benzamide (22)

SMILES: CC(C)(C)NCCCNC(=O)c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=FGCMNOQKWGVRBE-UHFFFAOYSA-N

Data: 10 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 154566   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methyl-lysine binding protein (53BP1) (Homo sapiens (Human))	BDBM154566 (N-(3-(Tert-butylamino)propyl)-4-(trifluoromethyl)b...) Show SMILES CC(C)(C)NCCCNC(=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C15H21F3N2O/c1-14(2,3)20-10-4-9-19-13(21)11-5-7-12(8-6-11)15(16,17)18/h5-8,20H,4,9-10H2,1-3H3,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.0	1,117.6
University of North Carolina at Chapel Hill					Assay Description In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...				ACS Chem Biol 10: 1072-81 (2015) Article DOI: 10.1021/cb500956g BindingDB Entry DOI: 10.7270/Q27S7MHJ
					More data for this Ligand-Target Pair
Chromobox protein homolog 7 (CBX7) (Homo sapiens (Human))	BDBM154566 (N-(3-(Tert-butylamino)propyl)-4-(trifluoromethyl)b...) Show SMILES CC(C)(C)NCCCNC(=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C15H21F3N2O/c1-14(2,3)20-10-4-9-19-13(21)11-5-7-12(8-6-11)15(16,17)18/h5-8,20H,4,9-10H2,1-3H3,(H,19,21)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.0	1,117.6
University of North Carolina at Chapel Hill					Assay Description In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...				ACS Chem Biol 10: 1072-81 (2015) Article DOI: 10.1021/cb500956g BindingDB Entry DOI: 10.7270/Q27S7MHJ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A (Homo sapiens (Human))	BDBM154566 (N-(3-(Tert-butylamino)propyl)-4-(trifluoromethyl)b...) Show SMILES CC(C)(C)NCCCNC(=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C15H21F3N2O/c1-14(2,3)20-10-4-9-19-13(21)11-5-7-12(8-6-11)15(16,17)18/h5-8,20H,4,9-10H2,1-3H3,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.0	1,117.6
University of North Carolina at Chapel Hill					Assay Description In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...				ACS Chem Biol 10: 1072-81 (2015) Article DOI: 10.1021/cb500956g BindingDB Entry DOI: 10.7270/Q27S7MHJ
					More data for this Ligand-Target Pair
PHD finger protein 1 (PHF1) (Homo sapiens (Human))	BDBM154566 (N-(3-(Tert-butylamino)propyl)-4-(trifluoromethyl)b...) Show SMILES CC(C)(C)NCCCNC(=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C15H21F3N2O/c1-14(2,3)20-10-4-9-19-13(21)11-5-7-12(8-6-11)15(16,17)18/h5-8,20H,4,9-10H2,1-3H3,(H,19,21)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.0	844.45
University of North Carolina at Chapel Hill					Assay Description In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...				ACS Chem Biol 10: 1072-81 (2015) Article DOI: 10.1021/cb500956g BindingDB Entry DOI: 10.7270/Q27S7MHJ
					More data for this Ligand-Target Pair
MBT domain-containing protein 1 (MBTD1) (Homo sapiens (Human))	BDBM154566 (N-(3-(Tert-butylamino)propyl)-4-(trifluoromethyl)b...) Show SMILES CC(C)(C)NCCCNC(=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C15H21F3N2O/c1-14(2,3)20-10-4-9-19-13(21)11-5-7-12(8-6-11)15(16,17)18/h5-8,20H,4,9-10H2,1-3H3,(H,19,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.0	571.3
University of North Carolina at Chapel Hill					Assay Description In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...				ACS Chem Biol 10: 1072-81 (2015) Article DOI: 10.1021/cb500956g BindingDB Entry DOI: 10.7270/Q27S7MHJ
					More data for this Ligand-Target Pair
PHD finger protein 23 (PHF23) (Homo sapiens (Human))	BDBM154566 (N-(3-(Tert-butylamino)propyl)-4-(trifluoromethyl)b...) Show SMILES CC(C)(C)NCCCNC(=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C15H21F3N2O/c1-14(2,3)20-10-4-9-19-13(21)11-5-7-12(8-6-11)15(16,17)18/h5-8,20H,4,9-10H2,1-3H3,(H,19,21)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.0	844.45
University of North Carolina at Chapel Hill					Assay Description In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...				ACS Chem Biol 10: 1072-81 (2015) Article DOI: 10.1021/cb500956g BindingDB Entry DOI: 10.7270/Q27S7MHJ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase (UHRF1) (Homo sapiens (Human))	BDBM154566 (N-(3-(Tert-butylamino)propyl)-4-(trifluoromethyl)b...) Show SMILES CC(C)(C)NCCCNC(=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C15H21F3N2O/c1-14(2,3)20-10-4-9-19-13(21)11-5-7-12(8-6-11)15(16,17)18/h5-8,20H,4,9-10H2,1-3H3,(H,19,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.0	571.3
University of North Carolina at Chapel Hill					Assay Description In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...				ACS Chem Biol 10: 1072-81 (2015) Article DOI: 10.1021/cb500956g BindingDB Entry DOI: 10.7270/Q27S7MHJ
					More data for this Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 1 (L3MBTL1) (Homo sapiens (Human))	BDBM154566 (N-(3-(Tert-butylamino)propyl)-4-(trifluoromethyl)b...) Show SMILES CC(C)(C)NCCCNC(=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C15H21F3N2O/c1-14(2,3)20-10-4-9-19-13(21)11-5-7-12(8-6-11)15(16,17)18/h5-8,20H,4,9-10H2,1-3H3,(H,19,21)	PDB KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.0	571.3
University of North Carolina at Chapel Hill					Assay Description In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...				ACS Chem Biol 10: 1072-81 (2015) Article DOI: 10.1021/cb500956g BindingDB Entry DOI: 10.7270/Q27S7MHJ
					More data for this Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3) (Homo sapiens (Human))	BDBM154566 (N-(3-(Tert-butylamino)propyl)-4-(trifluoromethyl)b...) Show SMILES CC(C)(C)NCCCNC(=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C15H21F3N2O/c1-14(2,3)20-10-4-9-19-13(21)11-5-7-12(8-6-11)15(16,17)18/h5-8,20H,4,9-10H2,1-3H3,(H,19,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.0	571.3
University of North Carolina at Chapel Hill					Assay Description In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...				ACS Chem Biol 10: 1072-81 (2015) Article DOI: 10.1021/cb500956g BindingDB Entry DOI: 10.7270/Q27S7MHJ
					More data for this Ligand-Target Pair
PHD finger protein 19 (PHF19) (Homo sapiens (Human))	BDBM154566 (N-(3-(Tert-butylamino)propyl)-4-(trifluoromethyl)b...) Show SMILES CC(C)(C)NCCCNC(=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C15H21F3N2O/c1-14(2,3)20-10-4-9-19-13(21)11-5-7-12(8-6-11)15(16,17)18/h5-8,20H,4,9-10H2,1-3H3,(H,19,21)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.0	844.45
University of North Carolina at Chapel Hill					Assay Description In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...				ACS Chem Biol 10: 1072-81 (2015) Article DOI: 10.1021/cb500956g BindingDB Entry DOI: 10.7270/Q27S7MHJ
					More data for this Ligand-Target Pair