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SMILES: CSc1cccc(NC(=O)[C@@H]2CCCN2S(=O)(=O)c2cccc(Cl)c2)c1

InChI Key: InChIKey=NPUOZBQFFCKVBZ-KRWDZBQOSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 154928   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM154928 (US9000029, 7) Show SMILES CSc1cccc(NC(=O)[C@@H]2CCCN2S(=O)(=O)c2cccc(Cl)c2)c1 Show InChI InChI=1S/C18H19ClN2O3S2/c1-25-15-7-3-6-14(12-15)20-18(22)17-9-4-10-21(17)26(23,24)16-8-2-5-13(19)11-16/h2-3,5-8,11-12,17H,4,9-10H2,1H3,(H,20,22)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	37
Actelion Pharmaceuticals Ltd. US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...				US Patent US9000029 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B3F
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM154928 (US9000029, 7) Show SMILES CSc1cccc(NC(=O)[C@@H]2CCCN2S(=O)(=O)c2cccc(Cl)c2)c1 Show InChI InChI=1S/C18H19ClN2O3S2/c1-25-15-7-3-6-14(12-15)20-18(22)17-9-4-10-21(17)26(23,24)16-8-2-5-13(19)11-16/h2-3,5-8,11-12,17H,4,9-10H2,1H3,(H,20,22)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	37
Actelion Pharmaceuticals Ltd. US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...				US Patent US9000029 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B3F
					More data for this Ligand-Target Pair