null
SMILES: N[C@H]1CN(CCc2cccc(c2)C(O)=O)C(=O)C[C@@H]1c1cc(F)c(F)cc1F
InChI Key: InChIKey=QXKPQSPVHRYOGI-KDOFPFPSSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM15515 (3-(2-((4R,5R)-5-amino-2-oxo-4-(2,4,5-trifluorophen...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 3.80 | -11.4 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
Abbott Laboratories | Assay Description The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas... | J Med Chem 50: 1983-7 (2007) Article DOI: 10.1021/jm061436d BindingDB Entry DOI: 10.7270/Q2VQ30XV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 9 (Homo sapiens (Human)) | BDBM15515 (3-(2-((4R,5R)-5-amino-2-oxo-4-(2,4,5-trifluorophen...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories | Assay Description The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas... | J Med Chem 50: 1983-7 (2007) Article DOI: 10.1021/jm061436d BindingDB Entry DOI: 10.7270/Q2VQ30XV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 8 (Homo sapiens (Human)) | BDBM15515 (3-(2-((4R,5R)-5-amino-2-oxo-4-(2,4,5-trifluorophen...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories | Assay Description The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas... | J Med Chem 50: 1983-7 (2007) Article DOI: 10.1021/jm061436d BindingDB Entry DOI: 10.7270/Q2VQ30XV | |||||||||||
More data for this Ligand-Target Pair |