BDBM155384 US9006282, Example 3, Compound 3
SMILES: COC1C[C@@H](C[C@@H](CCn2c(C(C)C)c(C(=O)Nc3ccccc3)c(c2-c2ccc(F)cc2)-c2ccccc2)O1)OC(=O)c1cccnc1
InChI Key: InChIKey=ZFYLYTBCONNVCQ-DOTKWZJKSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
HMG-CoA reductase (Rattus norvegicus (rat)) | BDBM155384 (US9006282, Example 3, Compound 3) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Redx Pharma Limited US Patent | Assay Description All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP... | US Patent US9006282 (2015) BindingDB Entry DOI: 10.7270/Q28K77T8 | |||||||||||
More data for this Ligand-Target Pair |