BDBM156236 US9018255, 3b
SMILES: CCOC(=O)CNC(=O)C(CC(C)C)NC(=O)C(=C)COC(=O)c1c(Cl)cccc1Cl
InChI Key: InChIKey=ZQEFBSNKAVWNJR-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Thioredoxin reductase 1, cytoplasmic (Homo sapiens (Human)) | BDBM156236 (US9018255, 3b) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | 7.6 | n/a |
Instytut Chemii Organicznej Polskiej Akademii Nauk; Warszawski Uniwersytet Medyczny US Patent | Assay Description The method of determining thioredoxin activity is based on the reduction of insulin by thioredoxin. Thioredoxin is reconstituted is by thioredoxin re... | US Patent US9018255 (2015) BindingDB Entry DOI: 10.7270/Q2VD6X6N | |||||||||||
More data for this Ligand-Target Pair |