BDBM15628 4-(4-(3-Chlorophenyl)-1H-pyrazol-3-yl)-N-(2-(pyridin-3-yl)-ethyl)-1H-pyrrole-2-carboxamide::4-[4-(3-chlorophenyl)-1H-pyrazol-3-yl]-N-[2-(pyridin-3-yl)ethyl]-1H-pyrrole-2-carboxamide::Pyrrole Carboxamide Analog 5n

SMILES: Clc1cccc(c1)-c1c[nH]nc1-c1c[nH]c(c1)C(=O)NCCc1cccnc1

InChI Key: InChIKey=QDUDWHMLOOZLSL-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15628   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM15628 (4-(4-(3-Chlorophenyl)-1H-pyrazol-3-yl)-N-(2-(pyrid...) Show SMILES Clc1cccc(c1)-c1c[nH]nc1-c1c[nH]c(c1)C(=O)NCCc1cccnc1 Show InChI InChI=1S/C21H18ClN5O/c22-17-5-1-4-15(9-17)18-13-26-27-20(18)16-10-19(25-12-16)21(28)24-8-6-14-3-2-7-23-11-14/h1-5,7,9-13,25H,6,8H2,(H,24,28)(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	330	-8.98	n/a	n/a	n/a	n/a	n/a	7.5	30
Vertex					Assay Description A coupled spectrophotometric assay was used in which ADP generated by ERK2 was converted to ATP by pyruvate kinase with the production of pyruvate fr...				J Med Chem 50: 1280-7 (2007) Article DOI: 10.1021/jm061381f BindingDB Entry DOI: 10.7270/Q2BR8QFV
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM15628 (4-(4-(3-Chlorophenyl)-1H-pyrazol-3-yl)-N-(2-(pyrid...) Show SMILES Clc1cccc(c1)-c1c[nH]nc1-c1c[nH]c(c1)C(=O)NCCc1cccnc1 Show InChI InChI=1S/C21H18ClN5O/c22-17-5-1-4-15(9-17)18-13-26-27-20(18)16-10-19(25-12-16)21(28)24-8-6-14-3-2-7-23-11-14/h1-5,7,9-13,25H,6,8H2,(H,24,28)(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vertex					Assay Description A coupled spectrophotometric assay was used in which ADP generated by JNK3 was converted to ATP by pyruvate kinase with the production of pyruvate fr...				J Med Chem 50: 1280-7 (2007) Article DOI: 10.1021/jm061381f BindingDB Entry DOI: 10.7270/Q2BR8QFV
					More data for this Ligand-Target Pair