BDBM156366 US9018371, 6
SMILES: COc1ccc(Cl)cc1CNc1nc(Cl)nc2n(cnc12)[C@@H]1SCC(O)[C@@H]1O
InChI Key: InChIKey=LJLMHEFJMXWPHX-ALWGXXCGSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM156366 (US9018371, 6) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 12.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
FM Therapeutics Co., Ltd.; The United States of America, As Represented by the Secretary, Department of Health and Human Services, The Office of Technology Transfer, National Institutes of Health US Patent | Assay Description CHO cells (ATCC No. CCL-61), in which A1 and A3 adenosine receptors were expressed, were cultured in F-12 media (Gibco, U.S.A.) supplemented with 10%... | US Patent US9018371 (2015) BindingDB Entry DOI: 10.7270/Q2G44P1K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM156366 (US9018371, 6) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 4.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
FM Therapeutics Co., Ltd.; The United States of America, As Represented by the Secretary, Department of Health and Human Services, The Office of Technology Transfer, National Institutes of Health US Patent | Assay Description CHO cells (ATCC No. CCL-61), in which A1 and A3 adenosine receptors were expressed, were cultured in F-12 media (Gibco, U.S.A.) supplemented with 10%... | US Patent US9018371 (2015) BindingDB Entry DOI: 10.7270/Q2G44P1K | |||||||||||
More data for this Ligand-Target Pair |