BDBM156741 US9029559, 161

SMILES: Cc1cccc(c1C)-c1cccc(n1)C(=O)N[C@@H](CC(O)=O)c1ccccc1C

InChI Key: InChIKey=MDARWIHWEQROKT-QFIPXVFZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 156741   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin A (CTSA) (Homo sapiens (Human))	BDBM156741 (US9029559, 161) Show SMILES Cc1cccc(c1C)-c1cccc(n1)C(=O)N[C@@H](CC(O)=O)c1ccccc1C Show InChI InChI=1S/C24H24N2O3/c1-15-9-6-11-19(17(15)3)20-12-7-13-21(25-20)24(29)26-22(14-23(27)28)18-10-5-4-8-16(18)2/h4-13,22H,14H2,1-3H3,(H,26,29)(H,27,28)/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	29.4	n/a	n/a	n/a	n/a	5.5	25
SANOFI US Patent					Assay Description The activated cathepsin A was diluted in assay buffer (25 mM MES, pH 5.5, containing 5 mM DTT) and mixed with the test compound (dissolved in assay b...				US Patent US9029559 (2015) BindingDB Entry DOI: 10.7270/Q22V2DW7
					More data for this Ligand-Target Pair