BDBM15759 4,7 Diazaindole 22::4-[7-(4-fluorophenyl)-5H-pyrrolo[2,3-b]pyrazin-6-yl]pyridine

SMILES: Fc1ccc(cc1)-c1c([nH]c2nccnc12)-c1ccncc1

InChI Key: InChIKey=LXTFKKVJJMDQNR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15759   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sensor protein kinase WalK (Staphylococcus aureus)	BDBM15759 (4,7 Diazaindole 22 | 4-[7-(4-fluorophenyl)-5H-pyrr...) Show SMILES Fc1ccc(cc1)-c1c([nH]c2nccnc12)-c1ccncc1 Show InChI InChI=1S/C17H11FN4/c18-13-3-1-11(2-4-13)14-15(12-5-7-19-8-6-12)22-17-16(14)20-9-10-21-17/h1-10H,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	9.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae VicK autophosphorylation using compound at non-aggregating concentration after 30 mins in presence of [gamma-3...				Bioorg Med Chem 26: 5322-5326 (2018) Article DOI: 10.1016/j.bmc.2018.04.047 BindingDB Entry DOI: 10.7270/Q2R2143H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15759 (4,7 Diazaindole 22 | 4-[7-(4-fluorophenyl)-5H-pyrr...) Show SMILES Fc1ccc(cc1)-c1c([nH]c2nccnc12)-c1ccncc1 Show InChI InChI=1S/C17H11FN4/c18-13-3-1-11(2-4-13)14-15(12-5-7-19-8-6-12)22-17-16(14)20-9-10-21-17/h1-10H,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	7.4	30
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 46: 4702-13 (2003) Article DOI: 10.1021/jm0301787 BindingDB Entry DOI: 10.7270/Q2ZG6QHT
					More data for this Ligand-Target Pair