BDBM158299 US9029370, 93

SMILES: FC(F)Oc1ccc(cc1)-n1cc(cn1)C(=O)Nc1ccc([C@@H]2CNCCO2)c(Cl)c1

InChI Key: InChIKey=QIOOAVAQJJQTIU-IBGZPJMESA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 158299   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trace amine-associated receptor 1 (TAAR1) (Mus musculus (Mouse))	BDBM158299 (US9029370, 93) Show SMILES FC(F)Oc1ccc(cc1)-n1cc(cn1)C(=O)Nc1ccc([C@@H]2CNCCO2)c(Cl)c1 |r| Show InChI InChI=1S/C21H19ClF2N4O3/c22-18-9-14(1-6-17(18)19-11-25-7-8-30-19)27-20(29)13-10-26-28(12-13)15-2-4-16(5-3-15)31-21(23)24/h1-6,9-10,12,19,21,25H,7-8,11H2,(H,27,29)/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.5	-13.2	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description Membrane Preparation and Radioligand Binding. HEK-293 cells stably expressing mouse TAA 1 were maintained at 37 C and 5% C02 in DMEM high glucose med...				US Patent US9029370 (2015) BindingDB Entry DOI: 10.7270/Q2NP235N
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (TAAR1) (Rattus norvegicus (Rat))	BDBM158299 (US9029370, 93) Show SMILES FC(F)Oc1ccc(cc1)-n1cc(cn1)C(=O)Nc1ccc([C@@H]2CNCCO2)c(Cl)c1 |r| Show InChI InChI=1S/C21H19ClF2N4O3/c22-18-9-14(1-6-17(18)19-11-25-7-8-30-19)27-20(29)13-10-26-28(12-13)15-2-4-16(5-3-15)31-21(23)24/h1-6,9-10,12,19,21,25H,7-8,11H2,(H,27,29)/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.20	-12.7	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat inac...				US Patent US9029370 (2015) BindingDB Entry DOI: 10.7270/Q2NP235N
					More data for this Ligand-Target Pair