null

SMILES: Clc1ccc(s1)-c1cc(Cn2c(cc3ccccc23)C(=O)N2CCC(CC2)Nc2ccncc2)no1

InChI Key: InChIKey=MGMRQNKJMRCNMF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15846   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM15846 (2-carboxyindole-based inhibitor 31 | N-{1-[(1-{[5-...) Show SMILES Clc1ccc(s1)-c1cc(Cn2c(cc3ccccc23)C(=O)N2CCC(CC2)Nc2ccncc2)no1 Show InChI InChI=1S/C27H24ClN5O2S/c28-26-6-5-25(36-26)24-16-21(31-35-24)17-33-22-4-2-1-3-18(22)15-23(33)27(34)32-13-9-20(10-14-32)30-19-7-11-29-12-8-19/h1-8,11-12,15-16,20H,9-10,13-14,17H2,(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH					Assay Description The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...				Bioorg Med Chem Lett 14: 4197-201 (2004) Article DOI: 10.1016/j.bmcl.2004.06.019 BindingDB Entry DOI: 10.7270/Q2610XKM
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM15846 (2-carboxyindole-based inhibitor 31 | N-{1-[(1-{[5-...) Show SMILES Clc1ccc(s1)-c1cc(Cn2c(cc3ccccc23)C(=O)N2CCC(CC2)Nc2ccncc2)no1 Show InChI InChI=1S/C27H24ClN5O2S/c28-26-6-5-25(36-26)24-16-21(31-35-24)17-33-22-4-2-1-3-18(22)15-23(33)27(34)32-13-9-20(10-14-32)30-19-7-11-29-12-8-19/h1-8,11-12,15-16,20H,9-10,13-14,17H2,(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH					Assay Description The inhibitory effect of test compound for human thrombin was determined by using the chromogenic substrates S-2366. The hydrolysis rates of chromoge...				Bioorg Med Chem Lett 14: 4197-201 (2004) Article DOI: 10.1016/j.bmcl.2004.06.019 BindingDB Entry DOI: 10.7270/Q2610XKM
					More data for this Ligand-Target Pair