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SMILES: CC(C)N1CCC(CC1)NC(=O)c1cc2ccccc2n1Cc1ccc(Cl)cc1

InChI Key: InChIKey=FXQMOQVEXWRJHX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15852   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))		BDBM15852
PNG
(1-[(4-chlorophenyl)methyl]-N-[1-(propan-2-yl)piper...)
Show SMILES CC(C)N1CCC(CC1)NC(=O)c1cc2ccccc2n1Cc1ccc(Cl)cc1
Show InChI InChI=1S/C24H28ClN3O/c1-17(2)27-13-11-21(12-14-27)26-24(29)23-15-19-5-3-4-6-22(19)28(23)16-18-7-9-20(25)10-8-18/h3-10,15,17,21H,11-14,16H2,1-2H3,(H,26,29)
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Article
PubMed
 2.50E+3 -7.64n/an/an/an/an/a7.825



Aventis Pharma Deutschland GmbH



Assay Description
The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...

Bioorg Med Chem Lett 14: 4191-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.020
BindingDB Entry DOI: 10.7270/Q22805WQ
More data for this
Ligand-Target Pair