BDBM158565 US9034866, 40

SMILES: NC(=O)c1nc-2c(CCOc3cc(F)c(cc-23)C#CC2(O)CCCC2)s1

InChI Key: InChIKey=AESXUDZAHNFUCG-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 158565   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 14 (Homo sapiens (Human))	BDBM158565 (US9034866, 40) Show SMILES NC(=O)c1nc-2c(CCOc3cc(F)c(cc-23)C#CC2(O)CCCC2)s1 Show InChI InChI=1S/C19H17FN2O3S/c20-13-10-14-12(9-11(13)3-7-19(24)5-1-2-6-19)16-15(4-8-25-14)26-18(22-16)17(21)23/h9-10,24H,1-2,4-6,8H2,(H2,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
Genentech, Inc. US Patent					Assay Description The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5'-triphosphate (ATP) was monitored u...				US Patent US9034866 (2015) BindingDB Entry DOI: 10.7270/Q2GX49B0
					More data for this Ligand-Target Pair