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SMILES: CC(C)N1CCC(CC1)NC(=O)c1cc2ccccc2n1Cc1cnc(s1)-c1ccc(Cl)s1

InChI Key: InChIKey=DBUBLUXPBHYRHZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15864   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))		BDBM15864
PNG
(1-{[2-(5-chlorothiophen-2-yl)-1,3-thiazol-5-yl]met...)
Show SMILES CC(C)N1CCC(CC1)NC(=O)c1cc2ccccc2n1Cc1cnc(s1)-c1ccc(Cl)s1
Show InChI InChI=1S/C25H27ClN4OS2/c1-16(2)29-11-9-18(10-12-29)28-24(31)21-13-17-5-3-4-6-20(17)30(21)15-19-14-27-25(32-19)22-7-8-23(26)33-22/h3-8,13-14,16,18H,9-12,15H2,1-2H3,(H,28,31)
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Article
PubMed
 57 -9.88n/an/an/an/an/a7.825



Aventis Pharma Deutschland GmbH



Assay Description
The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...

Bioorg Med Chem Lett 14: 4191-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.020
BindingDB Entry DOI: 10.7270/Q22805WQ
More data for this
Ligand-Target Pair