BDBM159121 US10195186, Example 9::US9682967, 9

SMILES: Cc1cc(NC(=O)c2ccc(cc2C(O)=O)C(F)(F)F)ccn1

InChI Key: InChIKey=DALXWGIVGGKECN-UHFFFAOYSA-N

Data: 2 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 159121   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neurotensin receptor 3 (Homo sapiens (Human))	BDBM159121 (US10195186, Example 9 | US9682967, 9) Show SMILES Cc1cc(NC(=O)c2ccc(cc2C(O)=O)C(F)(F)F)ccn1 Show InChI InChI=1S/C15H11F3N2O3/c1-8-6-10(4-5-19-8)20-13(21)11-3-2-9(15(16,17)18)7-12(11)14(22)23/h2-7H,1H3,(H,22,23)(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	667	n/a	700	n/a	n/a	n/a	n/a	7.4	n/a
H. Lundbeck A/S US Patent					Assay Description The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...				US Patent US9682967 (2017) BindingDB Entry DOI: 10.7270/Q22805SC
					More data for this Ligand-Target Pair
Neurotensin receptor 3 (Homo sapiens (Human))	BDBM159121 (US10195186, Example 9 | US9682967, 9) Show SMILES Cc1cc(NC(=O)c2ccc(cc2C(O)=O)C(F)(F)F)ccn1 Show InChI InChI=1S/C15H11F3N2O3/c1-8-6-10(4-5-19-8)20-13(21)11-3-2-9(15(16,17)18)7-12(11)14(22)23/h2-7H,1H3,(H,22,23)(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	667	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...				US Patent US10195186 (2019) BindingDB Entry DOI: 10.7270/Q2474CZW
					More data for this Ligand-Target Pair
Neurotensin receptor 3 (Homo sapiens (Human))	BDBM159121 (US10195186, Example 9 | US9682967, 9) Show SMILES Cc1cc(NC(=O)c2ccc(cc2C(O)=O)C(F)(F)F)ccn1 Show InChI InChI=1S/C15H11F3N2O3/c1-8-6-10(4-5-19-8)20-13(21)11-3-2-9(15(16,17)18)7-12(11)14(22)23/h2-7H,1H3,(H,22,23)(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...				US Patent US10195186 (2019) BindingDB Entry DOI: 10.7270/Q2474CZW
					More data for this Ligand-Target Pair