BDBM159245 US9034874, 1.2

SMILES: CC(C)N1CCN(CC1)C(=O)OC1CCN(CC1)c1ccc(=O)n(C)n1

InChI Key: InChIKey=JXFIKXGRFYNISW-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 159245   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM159245 (US9034874, 1.2) Show SMILES CC(C)N1CCN(CC1)C(=O)OC1CCN(CC1)c1ccc(=O)n(C)n1 Show InChI InChI=1S/C18H29N5O3/c1-14(2)21-10-12-23(13-11-21)18(25)26-15-6-8-22(9-7-15)16-4-5-17(24)20(3)19-16/h4-5,14-15H,6-13H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description The potency of compounds of the invention as H3 receptor antagonists can be assessed by measuring the blockade of (R)-alpha-methylhistamine-mediated ...				US Patent US9034874 (2015) BindingDB Entry DOI: 10.7270/Q2C82819
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM159245 (US9034874, 1.2) Show SMILES CC(C)N1CCN(CC1)C(=O)OC1CCN(CC1)c1ccc(=O)n(C)n1 Show InChI InChI=1S/C18H29N5O3/c1-14(2)21-10-12-23(13-11-21)18(25)26-15-6-8-22(9-7-15)16-4-5-17(24)20(3)19-16/h4-5,14-15H,6-13H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	31	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
NOVARTIS AG US Patent					Assay Description The affinity of compounds of the invention to the H3 receptor can be assessed by measuring displacement of binding of the radioligand [3H]-N-alpha -M...				US Patent US9034874 (2015) BindingDB Entry DOI: 10.7270/Q2C82819
					More data for this Ligand-Target Pair