BDBM159379 US10093663, Example 17-8::US9682968, Example-17-8

SMILES: COc1cc(C)c2[nH]ccc2c1CN1CCCC[C@H]1c1ccc(cc1F)C(O)=O

InChI Key:

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 159379   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement factor B (Homo sapiens (Human))	BDBM159379 (US10093663, Example 17-8 | US9682968, Example-17-8) Show SMILES COc1cc(C)c2[nH]ccc2c1CN1CCCC[C@H]1c1ccc(cc1F)C(O)=O |r| Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...				US Patent US10093663 (2018) BindingDB Entry DOI: 10.7270/Q2DF6T75
					More data for this Ligand-Target Pair
Complement factor B (Homo sapiens (Human))	BDBM159379 (US10093663, Example 17-8 | US9682968, Example-17-8) Show SMILES COc1cc(C)c2[nH]ccc2c1CN1CCCC[C@H]1c1ccc(cc1F)C(O)=O |r| Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0700	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...				US Patent US9682968 (2017) BindingDB Entry DOI: 10.7270/Q2XG9P9J
					More data for this Ligand-Target Pair