BindingDB PrimarySearch_ki

Search and Browse
- Target
- Compound
- Special tools
- Citation
- Special Data Sets
- Other Databases
  - PDB 85% 100% Seq ID
  - UniProtKB/Swiss-Prot
  - UniProtKB/TrEMBL
  - PubMed
Download
- All Compounds & Data
- Target Names &
  - Ki IC50 Kd EC50
  - ΔG° ΔH° -TΔS°
Enter Data

BDBM159566 US10093663, Example 17-18::US9682968, Example-17-18

SMILES: COC1CCN(Cc2c(cc(C)c3[nH]ccc23)C2CC2)C(C1)c1ccc(nc1)C(O)=O

InChI Key:

Data: 2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 159566
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Complement factor B (Homo sapiens (Human))	BDBM159566 (US10093663, Example 17-18 \| US9682968, Example-17-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...				US Patent US10093663 (2018) BindingDB Entry DOI: 10.7270/Q2DF6T75
Novartis AG US Patent					More data for this Ligand-Target Pair
Complement factor B (Homo sapiens (Human))	BDBM159566 (US10093663, Example 17-18 \| US9682968, Example-17-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0300	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...				US Patent US9682968 (2017) BindingDB Entry DOI: 10.7270/Q2XG9P9J
Novartis AG US Patent					More data for this Ligand-Target Pair