BDBM159694 US9035059, 14-16

SMILES: COc1ccc(NS(=O)(=O)c2ccc3CN(Cc3c2)C(=O)Nc2ccc(cc2)C(C)(C)C)c(F)c1

InChI Key: InChIKey=GQLKMXITVGKKIC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 159694   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA:monoacylglycerol acyltransferase 2 (MOGAT2) (Homo sapiens (Human))	BDBM159694 (US9035059, 14-16) Show SMILES COc1ccc(NS(=O)(=O)c2ccc3CN(Cc3c2)C(=O)Nc2ccc(cc2)C(C)(C)C)c(F)c1 Show InChI InChI=1S/C26H28FN3O4S/c1-26(2,3)19-6-8-20(9-7-19)28-25(31)30-15-17-5-11-22(13-18(17)16-30)35(32,33)29-24-12-10-21(34-4)14-23(24)27/h5-14,29H,15-16H2,1-4H3,(H,28,31)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	164	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant MGAT2 assessed as reduction in enzyme-mediated deacylation of oleoyl-CoA incubated for 20 mins by CPM dye based fluor...				Bioorg Med Chem 23: 5922-31 (2015) BindingDB Entry DOI: 10.7270/Q2639RJ6
					More data for this Ligand-Target Pair
Acyl-CoA:monoacylglycerol acyltransferase 2 (MOGAT2) (Homo sapiens (Human))	BDBM159694 (US9035059, 14-16) Show SMILES COc1ccc(NS(=O)(=O)c2ccc3CN(Cc3c2)C(=O)Nc2ccc(cc2)C(C)(C)C)c(F)c1 Show InChI InChI=1S/C26H28FN3O4S/c1-26(2,3)19-6-8-20(9-7-19)28-25(31)30-15-17-5-11-22(13-18(17)16-30)35(32,33)29-24-12-10-21(34-4)14-23(24)27/h5-14,29H,15-16H2,1-4H3,(H,28,31)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	164	n/a	n/a	n/a	n/a	n/a	n/a
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair