BDBM159718 US9035059, 18-25

SMILES: CC(C)(C)c1ccc(NC(=O)N2Cc3ccc(cc3C2)S(=O)(=O)Nc2ccc(OCCCCOc3ccccc3)cc2F)cc1

InChI Key: InChIKey=DJUJJMWABHVRMY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 159718   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA:monoacylglycerol acyltransferase 2 (MOGAT2) (Homo sapiens (Human))	BDBM159718 (US9035059, 18-25) Show SMILES CC(C)(C)c1ccc(NC(=O)N2Cc3ccc(cc3C2)S(=O)(=O)Nc2ccc(OCCCCOc3ccccc3)cc2F)cc1 Show InChI InChI=1S/C35H38FN3O5S/c1-35(2,3)27-12-14-28(15-13-27)37-34(40)39-23-25-11-17-31(21-26(25)24-39)45(41,42)38-33-18-16-30(22-32(33)36)44-20-8-7-19-43-29-9-5-4-6-10-29/h4-6,9-18,21-22,38H,7-8,19-20,23-24H2,1-3H3,(H,37,40)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair