Found 3 hits for monomerid = 15978 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Mitogen-activated protein kinase 8
(Homo sapiens (Human)) | BDBM15978
(2-({2-[(3-hydroxyphenyl)amino]pyrimidin-4-yl}amino...)Show InChI InChI=1S/C17H15N5O2/c18-16(24)13-6-1-2-7-14(13)21-15-8-9-19-17(22-15)20-11-4-3-5-12(23)10-11/h1-10,23H,(H2,18,24)(H2,19,20,21,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MMDB PC cid PC sid PDB UniChem
Similars
| DrugBank MMDB PDB Article PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | 7.2 | 20 |
Abbott Laboratories
| Assay Description In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm... |
Bioorg Med Chem Lett 17: 668-72 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.093 BindingDB Entry DOI: 10.7270/Q2J964N4 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Mitogen-activated protein kinase 8
(Homo sapiens (Human)) | BDBM15978
(2-({2-[(3-hydroxyphenyl)amino]pyrimidin-4-yl}amino...)Show InChI InChI=1S/C17H15N5O2/c18-16(24)13-6-1-2-7-14(13)21-15-8-9-19-17(22-15)20-11-4-3-5-12(23)10-11/h1-10,23H,(H2,18,24)(H2,19,20,21,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank MMDB PC cid PC sid PDB UniChem
Similars
| DrugBank MMDB PDB PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Semmelweis University
Curated by ChEMBL
| Assay Description Inhibition of JNK1 (unknown origin) |
Bioorg Med Chem Lett 26: 424-8 (2016)
BindingDB Entry DOI: 10.7270/Q24T6M6J |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Mitogen-activated protein kinase 8
(Homo sapiens (Human)) | BDBM15978
(2-({2-[(3-hydroxyphenyl)amino]pyrimidin-4-yl}amino...)Show InChI InChI=1S/C17H15N5O2/c18-16(24)13-6-1-2-7-14(13)21-15-8-9-19-17(22-15)20-11-4-3-5-12(23)10-11/h1-10,23H,(H2,18,24)(H2,19,20,21,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank MMDB PC cid PC sid PDB UniChem
Similars
| DrugBank MMDB PDB PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Semmelweis University
Curated by ChEMBL
| Assay Description Inhibition of JNK1alpha1 (unknown origin) |
Bioorg Med Chem Lett 26: 424-8 (2016)
BindingDB Entry DOI: 10.7270/Q24T6M6J |
More data for this Ligand-Target Pair | 3D Structure (crystal) |