BDBM161468 US9108978, 6.09
SMILES: Cc1ccc2oc(=O)n(CCCCn3cc(CCCCC[C@@H]4SC[C@@H]5NC(=O)N[C@H]45)nn3)c2c1
InChI Key: InChIKey=LIWDYWLHGFRYPL-NYVOZVTQSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Biotin ligase (Staphylococcus aureus) | BDBM161468 (US9108978, 6.09) | PDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | PDB US Patent | 90 | -9.99 | 530 | n/a | n/a | n/a | n/a | 8.0 | 37 |
Monash University; Adelaide Research & Innovation Pty Ltd US Patent | Assay Description Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol... | US Patent US9108978 (2015) BindingDB Entry DOI: 10.7270/Q2T43RVW | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
BirA Bifunctional Protein (Escherichia coli) | BDBM161468 (US9108978, 6.09) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | US Patent | >3.00E+4 | >-6.41 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
Monash University; Adelaide Research & Innovation Pty Ltd US Patent | Assay Description Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol... | US Patent US9108978 (2015) BindingDB Entry DOI: 10.7270/Q2T43RVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BirA Bifunctional Protein (Escherichia coli) | BDBM161468 (US9108978, 6.09) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | US Patent | >3.00E+4 | >-6.41 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
Monash University; Adelaide Research & Innovation Pty Ltd US Patent | Assay Description Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol... | US Patent US9108978 (2015) BindingDB Entry DOI: 10.7270/Q2T43RVW | |||||||||||
More data for this Ligand-Target Pair |