BDBM161469 US9108978, 6.07
SMILES: O=C1N[C@H]2CS[C@@H](CCCCCc3cn(CCCCOc4ccc5ccccc5c4)nn3)[C@H]2N1
InChI Key: InChIKey=PLGWUMURZLHGNO-SDHOMARFSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bifunctional ligase/repressor BirA (Staphylococcus aureus) | BDBM161469 (US9108978, 6.07) | PDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.17E+3 | -8.41 | 7.00E+3 | n/a | n/a | n/a | n/a | 8.0 | 37 |
Monash University; Adelaide Research & Innovation Pty Ltd US Patent | Assay Description Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol... | US Patent US9108978 (2015) BindingDB Entry DOI: 10.7270/Q2T43RVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional ligase/repressor BirA (Escherichia coli) | BDBM161469 (US9108978, 6.07) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | >3.00E+4 | >-6.41 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
Monash University; Adelaide Research & Innovation Pty Ltd US Patent | Assay Description Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol... | US Patent US9108978 (2015) BindingDB Entry DOI: 10.7270/Q2T43RVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional ligase/repressor BirA (Escherichia coli) | BDBM161469 (US9108978, 6.07) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | >3.00E+4 | >-6.41 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
Monash University; Adelaide Research & Innovation Pty Ltd US Patent | Assay Description Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol... | US Patent US9108978 (2015) BindingDB Entry DOI: 10.7270/Q2T43RVW | |||||||||||
More data for this Ligand-Target Pair |