BDBM16151 (2S)-2-[benzyl({4-chloro-1-[(diaminomethylidene)amino]isoquinoline-7-})sulfonamido]propanoic acid::substituted glycine deriv. 25

SMILES: [#6]-[#6@H](-[#7](-[#6]-c1ccccc1)S(=O)(=O)c1ccc2c(Cl)cnc(\[#7]=[#6](/[#7])-[#7])c2c1)-[#6](-[#8])=O

InChI Key: InChIKey=YQUVIYVFJDEFDB-LBPRGKRZSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 16151   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM16151 ((2S)-2-[benzyl({4-chloro-1-[(diaminomethylidene)am...) Show SMILES [#6]-[#6@H](-[#7](-[#6]-c1ccccc1)S(=O)(=O)c1ccc2c(Cl)cnc(\[#7]=[#6](/[#7])-[#7])c2c1)-[#6](-[#8])=O |r| Show InChI InChI=1S/C20H20ClN5O4S/c1-12(19(27)28)26(11-13-5-3-2-4-6-13)31(29,30)14-7-8-15-16(9-14)18(25-20(22)23)24-10-17(15)21/h2-10,12H,11H2,1H3,(H,27,28)(H4,22,23,24,25)/t12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...				J Med Chem 50: 2341-51 (2007) Article DOI: 10.1021/jm061066t BindingDB Entry DOI: 10.7270/Q27S7M18
					More data for this Ligand-Target Pair
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM16151 ((2S)-2-[benzyl({4-chloro-1-[(diaminomethylidene)am...) Show SMILES [#6]-[#6@H](-[#7](-[#6]-c1ccccc1)S(=O)(=O)c1ccc2c(Cl)cnc(\[#7]=[#6](/[#7])-[#7])c2c1)-[#6](-[#8])=O |r| Show InChI InChI=1S/C20H20ClN5O4S/c1-12(19(27)28)26(11-13-5-3-2-4-6-13)31(29,30)14-7-8-15-16(9-14)18(25-20(22)23)24-10-17(15)21/h2-10,12H,11H2,1H3,(H,27,28)(H4,22,23,24,25)/t12-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...				J Med Chem 50: 2341-51 (2007) Article DOI: 10.1021/jm061066t BindingDB Entry DOI: 10.7270/Q27S7M18
					More data for this Ligand-Target Pair