BDBM161942 US9682991, 5

SMILES: CN(C)C1CCN(CC1)c1nn2c(nnc2c2OCCN(C)c12)-c1cccc(OC(F)(F)F)c1

InChI Key: InChIKey=IAYHXSKNPQYTOD-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 161942   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161942 (US9682991, 5) Show SMILES CN(C)C1CCN(CC1)c1nn2c(nnc2c2OCCN(C)c12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C22H26F3N7O2/c1-29(2)15-7-9-31(10-8-15)20-17-18(33-12-11-30(17)3)21-27-26-19(32(21)28-20)14-5-4-6-16(13-14)34-22(23,24)25/h4-6,13,15H,7-12H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM161942 (US9682991, 5) Show SMILES CN(C)C1CCN(CC1)c1nn2c(nnc2c2OCCN(C)c12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C22H26F3N7O2/c1-29(2)15-7-9-31(10-8-15)20-17-18(33-12-11-30(17)3)21-27-26-19(32(21)28-20)14-5-4-6-16(13-14)34-22(23,24)25/h4-6,13,15H,7-12H2,1-3H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-3 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM161942 (US9682991, 5) Show SMILES CN(C)C1CCN(CC1)c1nn2c(nnc2c2OCCN(C)c12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C22H26F3N7O2/c1-29(2)15-7-9-31(10-8-15)20-17-18(33-12-11-30(17)3)21-27-26-19(32(21)28-20)14-5-4-6-16(13-14)34-22(23,24)25/h4-6,13,15H,7-12H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-2 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair