BDBM161990 US9682991, 39

SMILES: CC1COc2c(N1C)c(NCC1CCN(C)CC1)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1

InChI Key: InChIKey=IOBGPTAILQUDSL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 161990   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM161990 (US9682991, 39) Show SMILES CC1COc2c(N1C)c(NCC1CCN(C)CC1)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C23H28F3N7O2/c1-14-13-34-19-18(32(14)3)20(27-12-15-7-9-31(2)10-8-15)30-33-21(28-29-22(19)33)16-5-4-6-17(11-16)35-23(24,25)26/h4-6,11,14-15H,7-10,12-13H2,1-3H3,(H,27,30)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-2 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161990 (US9682991, 39) Show SMILES CC1COc2c(N1C)c(NCC1CCN(C)CC1)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C23H28F3N7O2/c1-14-13-34-19-18(32(14)3)20(27-12-15-7-9-31(2)10-8-15)30-33-21(28-29-22(19)33)16-5-4-6-17(11-16)35-23(24,25)26/h4-6,11,14-15H,7-10,12-13H2,1-3H3,(H,27,30)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair