BDBM161992 US9682991, 41

SMILES: CN1CCC(CNc2nn3c(nnc3c3OCCOc23)-c2cccc(OC(F)(F)F)c2)CC1

InChI Key: InChIKey=FGYKHKMPTZJJGG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 161992   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM161992 (US9682991, 41) Show SMILES CN1CCC(CNc2nn3c(nnc3c3OCCOc23)-c2cccc(OC(F)(F)F)c2)CC1 Show InChI InChI=1S/C21H23F3N6O3/c1-29-7-5-13(6-8-29)12-25-18-16-17(32-10-9-31-16)20-27-26-19(30(20)28-18)14-3-2-4-15(11-14)33-21(22,23)24/h2-4,11,13H,5-10,12H2,1H3,(H,25,28)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-2 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161992 (US9682991, 41) Show SMILES CN1CCC(CNc2nn3c(nnc3c3OCCOc23)-c2cccc(OC(F)(F)F)c2)CC1 Show InChI InChI=1S/C21H23F3N6O3/c1-29-7-5-13(6-8-29)12-25-18-16-17(32-10-9-31-16)20-27-26-19(30(20)28-18)14-3-2-4-15(11-14)33-21(22,23)24/h2-4,11,13H,5-10,12H2,1H3,(H,25,28)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair