BDBM161998 US9682991, 50

SMILES: CC1COc2c(N1C)c(nn1c(nnc21)-c1cccc(OC(F)(F)F)c1)N1CCC2(CC(N)C2)CC1

InChI Key: InChIKey=OCXWFMRMJBFTLR-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 161998   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161998 (US9682991, 50) Show SMILES CC1COc2c(N1C)c(nn1c(nnc21)-c1cccc(OC(F)(F)F)c1)N1CCC2(CC(N)C2)CC1 Show InChI InChI=1S/C24H28F3N7O2/c1-14-13-35-19-18(32(14)2)21(33-8-6-23(7-9-33)11-16(28)12-23)31-34-20(29-30-22(19)34)15-4-3-5-17(10-15)36-24(25,26)27/h3-5,10,14,16H,6-9,11-13,28H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair