BDBM162032 US9682991, 88

SMILES: CN1CCOc2c1c(NCC1CCN(CC3CC3)CC1)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1

InChI Key: InChIKey=JKYVSSSJTRXLHP-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 162032   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM162032 (US9682991, 88) Show SMILES CN1CCOc2c1c(NCC1CCN(CC3CC3)CC1)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C25H30F3N7O2/c1-33-11-12-36-21-20(33)22(29-14-16-7-9-34(10-8-16)15-17-5-6-17)32-35-23(30-31-24(21)35)18-3-2-4-19(13-18)37-25(26,27)28/h2-4,13,16-17H,5-12,14-15H2,1H3,(H,29,32)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM162032 (US9682991, 88) Show SMILES CN1CCOc2c1c(NCC1CCN(CC3CC3)CC1)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C25H30F3N7O2/c1-33-11-12-36-21-20(33)22(29-14-16-7-9-34(10-8-16)15-17-5-6-17)32-35-23(30-31-24(21)35)18-3-2-4-19(13-18)37-25(26,27)28/h2-4,13,16-17H,5-12,14-15H2,1H3,(H,29,32)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-3 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM162032 (US9682991, 88) Show SMILES CN1CCOc2c1c(NCC1CCN(CC3CC3)CC1)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C25H30F3N7O2/c1-33-11-12-36-21-20(33)22(29-14-16-7-9-34(10-8-16)15-17-5-6-17)32-35-23(30-31-24(21)35)18-3-2-4-19(13-18)37-25(26,27)28/h2-4,13,16-17H,5-12,14-15H2,1H3,(H,29,32)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-2 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair