BDBM162317 US9051313, 8
SMILES: C[C@H](n1cnnc1-c1nc(NC(=O)c2cc(c(cn2)N2CCCC2)-n2cnc(c2)C2CC2)cs1)C(F)(F)F
InChI Key: InChIKey=ITXKFABJUPGBQB-AWEZNQCLSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Apoptosis Signal-regulating Kinase 1 (ASK1) (Homo sapiens (Human)) | BDBM162317 (US9051313, 8) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Gildead Sciences, Inc. US Patent | Assay Description The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive... | US Patent US9051313 (2015) BindingDB Entry DOI: 10.7270/Q21N7ZVX | |||||||||||
More data for this Ligand-Target Pair |