BDBM162319 US10307427, Compound 10::US9051313, 10

SMILES: OC1CCN(C1)c1cnc(cc1-n1cnc(c1)C1CC1)C(=O)Nc1csc(n1)-c1nncn1C1CC1

InChI Key: InChIKey=OYQMZDDDXIGQFI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 162319   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM162319 (US10307427, Compound 10 | US9051313, 10) Show SMILES OC1CCN(C1)c1cnc(cc1-n1cnc(c1)C1CC1)C(=O)Nc1csc(n1)-c1nncn1C1CC1 Show InChI InChI=1S/C24H25N9O2S/c34-16-5-6-31(9-16)20-8-25-17(7-19(20)32-10-18(26-12-32)14-1-2-14)23(35)28-21-11-36-24(29-21)22-30-27-13-33(22)15-3-4-15/h7-8,10-16,34H,1-6,9H2,(H,28,35)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Washington University					Assay Description The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...				J Med Chem 52: 2188-91 (2009) BindingDB Entry DOI: 10.7270/Q2K64MD9
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM162319 (US10307427, Compound 10 | US9051313, 10) Show SMILES OC1CCN(C1)c1cnc(cc1-n1cnc(c1)C1CC1)C(=O)Nc1csc(n1)-c1nncn1C1CC1 Show InChI InChI=1S/C24H25N9O2S/c34-16-5-6-31(9-16)20-8-25-17(7-19(20)32-10-18(26-12-32)14-1-2-14)23(35)28-21-11-36-24(29-21)22-30-27-13-33(22)15-3-4-15/h7-8,10-16,34H,1-6,9H2,(H,28,35)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Gildead Sciences, Inc. US Patent					Assay Description The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...				US Patent US9051313 (2015) BindingDB Entry DOI: 10.7270/Q21N7ZVX
					More data for this Ligand-Target Pair