BDBM162869 US9056859, 39

SMILES: Fc1cc(CCN2CCN(CC2)C(=O)Cc2ccc(cc2)-n2cnnn2)ccc1[N+]#[C-]

InChI Key: InChIKey=JHTYVCIMKPTZPO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 162869   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Renal Outer Medullary Potassium (ROMK) (Rattus norvegicus (Rat))	BDBM162869 (US9056859, 39) Show SMILES Fc1cc(CCN2CCN(CC2)C(=O)Cc2ccc(cc2)-n2cnnn2)ccc1[N+]#[C-] Show InChI InChI=1S/C22H22FN7O/c1-24-21-7-4-18(14-20(21)23)8-9-28-10-12-29(13-11-28)22(31)15-17-2-5-19(6-3-17)30-16-25-26-27-30/h2-7,14,16H,8-13,15H2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	63	n/a	n/a	n/a	n/a	7.4	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Block of Kir1.1 (ROMKI) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...				US Patent US9056859 (2015) BindingDB Entry DOI: 10.7270/Q20P0XS0
					More data for this Ligand-Target Pair