BDBM162876 US9056859, 217
SMILES: Cc1c2COC(=O)c2ccc1[C@@H](O)CN1CCN(C2CC12)C(=O)Cc1ccc(nc1)-n1cnnn1
InChI Key: InChIKey=AUKXRHFMGMQRFC-CBNMVNINSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Renal Outer Medullary Potassium (ROMK) (Rattus norvegicus (Rat)) | BDBM162876 (US9056859, 217) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 56 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Block of Kir1.1 (ROMKI) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu... | US Patent US9056859 (2015) BindingDB Entry DOI: 10.7270/Q20P0XS0 | |||||||||||
More data for this Ligand-Target Pair |