BDBM163024 US9056865, A-151

SMILES: Cc1cc(F)cnc1-c1cc(ncc1Cl)N1CCN(CC1)C(=O)CCS(C)(=O)=O

InChI Key: InChIKey=GIXOJLMTQABZDC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 163024   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Smoothened homolog (Homo sapiens (Human))	BDBM163024 (US9056865, A-151) Show SMILES Cc1cc(F)cnc1-c1cc(ncc1Cl)N1CCN(CC1)C(=O)CCS(C)(=O)=O Show InChI InChI=1S/C19H22ClFN4O3S/c1-13-9-14(21)11-23-19(13)15-10-17(22-12-16(15)20)24-4-6-25(7-5-24)18(26)3-8-29(2,27)28/h9-12H,3-8H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.11	n/a	n/a	n/a	n/a	n/a	25
Pfizer Inc. US Patent					Assay Description For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...				US Patent US9056865 (2015) BindingDB Entry DOI: 10.7270/Q2R49PH7
					More data for this Ligand-Target Pair