BDBM163205 US9062045, 44
SMILES: COC1CCN(CC1)c1cnc2ccc(Sc3nnc4c(F)cc(cn34)-c3cnn(C)c3)cc2c1
InChI Key: InChIKey=ZRUDAHOWOHKQAO-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM163205 (US9062045, 44) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-F... | US Patent US9062045 (2015) BindingDB Entry DOI: 10.7270/Q23F4NDS | |||||||||||
More data for this Ligand-Target Pair |