BDBM163629 SR-3970

SMILES: CCCCCNNC(=O)c1ccc(Br)cc1

InChI Key: InChIKey=FSOILGKPVXNZLM-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 163629   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HDAC1/NCOR2 (Homo sapiens (Human))	BDBM163629 (SR-3970) Show SMILES CCCCCNNC(=O)c1ccc(Br)cc1 Show InChI InChI=1S/C12H17BrN2O/c1-2-3-4-9-14-15-12(16)10-5-7-11(13)8-6-10/h5-8,14H,2-4,9H2,1H3,(H,15,16)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida College of Medicine; Northwest Agriculture and Forestry University					Assay Description Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...				Chem Biol 22: 273-84 (2015) Article DOI: 10.1016/j.chembiol.2014.12.015 BindingDB Entry DOI: 10.7270/Q2TX3D48
					More data for this Ligand-Target Pair
HDAC2/NCOR2 (Homo sapiens (Human))	BDBM163629 (SR-3970) Show SMILES CCCCCNNC(=O)c1ccc(Br)cc1 Show InChI InChI=1S/C12H17BrN2O/c1-2-3-4-9-14-15-12(16)10-5-7-11(13)8-6-10/h5-8,14H,2-4,9H2,1H3,(H,15,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida College of Medicine; Northwest Agriculture and Forestry University					Assay Description Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...				Chem Biol 22: 273-84 (2015) Article DOI: 10.1016/j.chembiol.2014.12.015 BindingDB Entry DOI: 10.7270/Q2TX3D48
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM163629 (SR-3970) Show SMILES CCCCCNNC(=O)c1ccc(Br)cc1 Show InChI InChI=1S/C12H17BrN2O/c1-2-3-4-9-14-15-12(16)10-5-7-11(13)8-6-10/h5-8,14H,2-4,9H2,1H3,(H,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida College of Medicine; Northwest Agriculture and Forestry University					Assay Description Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...				Chem Biol 22: 273-84 (2015) Article DOI: 10.1016/j.chembiol.2014.12.015 BindingDB Entry DOI: 10.7270/Q2TX3D48
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM163629 (SR-3970) Show SMILES CCCCCNNC(=O)c1ccc(Br)cc1 Show InChI InChI=1S/C12H17BrN2O/c1-2-3-4-9-14-15-12(16)10-5-7-11(13)8-6-10/h5-8,14H,2-4,9H2,1H3,(H,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida College of Medicine; Northwest Agriculture and Forestry University					Assay Description Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...				Chem Biol 22: 273-84 (2015) Article DOI: 10.1016/j.chembiol.2014.12.015 BindingDB Entry DOI: 10.7270/Q2TX3D48
					More data for this Ligand-Target Pair
HDAC3/NCOR2 (Homo sapiens (Human))	BDBM163629 (SR-3970) Show SMILES CCCCCNNC(=O)c1ccc(Br)cc1 Show InChI InChI=1S/C12H17BrN2O/c1-2-3-4-9-14-15-12(16)10-5-7-11(13)8-6-10/h5-8,14H,2-4,9H2,1H3,(H,15,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	920	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida College of Medicine; Northwest Agriculture and Forestry University					Assay Description Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...				Chem Biol 22: 273-84 (2015) Article DOI: 10.1016/j.chembiol.2014.12.015 BindingDB Entry DOI: 10.7270/Q2TX3D48
					More data for this Ligand-Target Pair