BDBM163682 4‐Bromo‐N'‐cyclohexylidenebenzohydrazide (0151)

SMILES: Brc1ccc(cc1)-[#6](=O)-[#7]\[#7]=[#6]-1/[#6]-[#6]-[#6]-[#6]-[#6]-1

InChI Key: InChIKey=MYANQCMUOIPHBP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 163682   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
8-Oxoguanine DNA glycosylase-1 (OGG1) (Homo sapiens (Human))	BDBM163682 (4‐Bromo‐N'‐cyclohexylidenebe...) Show SMILES Brc1ccc(cc1)-[#6](=O)-[#7]\[#7]=[#6]-1/[#6]-[#6]-[#6]-[#6]-[#6]-1 Show InChI InChI=1S/C13H15BrN2O/c14-11-8-6-10(7-9-11)13(17)16-15-12-4-2-1-3-5-12/h6-9H,1-5H2,(H,16,17)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	7.5	37
Oregon Health & Science University					Assay Description A total of 4 µL of OGG1 (125 nM) was mixed with 1 µL of inhibitor. In a separate tube, 1 µL of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi...				ACS Chem Biol 10: 2334-43 (2015) Article DOI: 10.1021/acschembio.5b00452 BindingDB Entry DOI: 10.7270/Q22F7M6H
					More data for this Ligand-Target Pair
8-Oxoguanine DNA glycosylase-1 (OGG1) (Homo sapiens (Human))	BDBM163682 (4‐Bromo‐N'‐cyclohexylidenebe...) Show SMILES Brc1ccc(cc1)-[#6](=O)-[#7]\[#7]=[#6]-1/[#6]-[#6]-[#6]-[#6]-[#6]-1 Show InChI InChI=1S/C13H15BrN2O/c14-11-8-6-10(7-9-11)13(17)16-15-12-4-2-1-3-5-12/h6-9H,1-5H2,(H,16,17)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health & Science University					Assay Description Gel-based assays were performed by combining 4 µL of OGG1 (62.5 nM) with 1 µL of inhibitor or buffer. Substrate (5 µL, 50 nM) was added to bring the ...				ACS Chem Biol 10: 2334-43 (2015) Article DOI: 10.1021/acschembio.5b00452 BindingDB Entry DOI: 10.7270/Q22F7M6H
					More data for this Ligand-Target Pair