BDBM164411 US9066954, 34

SMILES: COc1cnc2c(NCc3nnc4ccc(nn34)-c3cc(C)no3)ccnc2c1

InChI Key: InChIKey=ZQCHASWRHDPHQK-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 164411   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM164411 (US9066954, 34) Show SMILES COc1cnc2c(NCc3nnc4ccc(nn34)-c3cc(C)no3)ccnc2c1 Show InChI InChI=1S/C19H16N8O2/c1-11-7-16(29-26-11)13-3-4-17-23-24-18(27(17)25-13)10-21-14-5-6-20-15-8-12(28-2)9-22-19(14)15/h3-9H,10H2,1-2H3,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	15.9	-10.7	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair