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SMILES: COc1ccc2c(OCc3nnc4ccc(nn34)C#CC(C)(C)O)ccnc2c1

InChI Key: InChIKey=RTXKWOSLTNPUAY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 164417   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM164417
PNG
(US9066954, 50)
Show SMILES COc1ccc2c(OCc3nnc4ccc(nn34)C#CC(C)(C)O)ccnc2c1
Show InChI InChI=1S/C21H19N5O3/c1-21(2,27)10-8-14-4-7-19-23-24-20(26(19)25-14)13-29-18-9-11-22-17-12-15(28-3)5-6-16(17)18/h4-7,9,11-12,27H,13H2,1-3H3
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Similars
US Patent
 23.8 -10.5n/an/an/an/an/a8.027



Amgen Inc.

US Patent


Assay Description
A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...

US Patent US9066954 (2015)


BindingDB Entry DOI: 10.7270/Q2N878JD
More data for this
Ligand-Target Pair