BDBM164441 US9066954, 118
SMILES: COc1cnc2ccc(cc2c1)[C@H](C)c1nnc2ccc(nn12)-c1ccccc1
InChI Key: InChIKey=FGXLXJKDJXTYSR-HNNXBMFYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM164441 (US9066954, 118) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 2.60 | -11.8 | n/a | n/a | n/a | n/a | n/a | 8.0 | 27 |
Amgen Inc. US Patent | Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri... | US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD | |||||||||||
More data for this Ligand-Target Pair |