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BDBM164457 US9066954, 202

SMILES: COc1ccc2c(OCc3nnc4ccc(nn34)-c3ccc4NC(=O)CCc4c3)ccnc2c1

InChI Key: InChIKey=DKSHTXQLMFKJRA-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 164457   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM164457
PNG
(US9066954, 202)
Show SMILES COc1ccc2c(OCc3nnc4ccc(nn34)-c3ccc4NC(=O)CCc4c3)ccnc2c1
Show InChI InChI=1S/C25H20N6O3/c1-33-17-4-5-18-21(13-17)26-11-10-22(18)34-14-24-29-28-23-8-7-20(30-31(23)24)16-2-6-19-15(12-16)3-9-25(32)27-19/h2,4-8,10-13H,3,9,14H2,1H3,(H,27,32)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
2.40 -11.8n/an/an/an/an/a8.027



Amgen Inc.

US Patent


Assay Description
A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...


US Patent US9066954 (2015)


BindingDB Entry DOI: 10.7270/Q2N878JD
More data for this
Ligand-Target Pair