BDBM164488 US9066954, 373
SMILES: Fc1cc(F)cc(c1)-c1ccc2nnc(CNc3ccnc4cc(OCCn5cncn5)cnc34)n2n1
InChI Key: InChIKey=YWAKXUWRHLXYJM-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM164488 (US9066954, 373) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.100 | -13.7 | n/a | n/a | n/a | n/a | n/a | 8.0 | 27 |
Amgen Inc. US Patent | Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri... | US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD | |||||||||||
More data for this Ligand-Target Pair |